Kazuyuki Matsushita Selected Research

poly-U binding splicing factor 60KDa

9/2017	FIR haplodeficiency promotes splicing to pyruvate kinase M2 in mice thymic lymphoma tissues revealed by six-plex tandem mass tag quantitative proteomic analysis.
1/2015	Gene therapy of c-myc suppressor FUSE-binding protein-interacting repressor by Sendai virus delivery prevents tracheal stenosis.
4/2014	Non-transmissible Sendai virus vector encoding c-myc suppressor FBP-interacting repressor for cancer therapy.
7/2013	Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.
2/2013	SAP155-mediated c-myc suppressor far-upstream element-binding protein-interacting repressor splicing variants are activated in colon cancer tissues.
6/2012	SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.
7/2011	Synergistic effect of non-transmissible Sendai virus vector encoding the c-myc suppressor FUSE-binding protein-interacting repressor plus cisplatin in the treatment of malignant pleural mesothelioma.
12/2009	[Clinical application of alternative splicing form of c-myc suppressor FUSE-binding protein-interacting repressor for cancer detection and treatment].
1/2009	c-myc suppressor FBP-interacting repressor for cancer diagnosis and therapy.
2/2006	An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis.

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Kazuyuki Matsushita Research Topics

Disease

44	Neoplasms (Cancer) 01/2022 - 07/2003
20	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 11/2002
9	Esophageal Neoplasms (Esophageal Cancer) 05/2018 - 11/2005
8	Esophageal Squamous Cell Carcinoma 12/2020 - 02/2006
7	Neoplasm Metastasis (Metastasis) 02/2020 - 11/2002
6	Stomach Neoplasms (Stomach Cancer) 02/2021 - 05/2011
4	Colonic Neoplasms (Colon Cancer) 04/2018 - 03/2011
4	Hepatocellular Carcinoma (Hepatoma) 01/2016 - 08/2008
3	Atherosclerosis 01/2021 - 12/2020
3	Ischemic Stroke 01/2021 - 12/2020
3	Chronic Renal Insufficiency 01/2021 - 04/2011
3	Lung Neoplasms (Lung Cancer) 01/2018 - 01/2014
3	Carcinogenesis 03/2015 - 02/2006
2	COVID-19 12/2021 - 08/2020
2	Biliary Tract Neoplasms (Biliary Tract Cancer) 08/2021 - 01/2012
2	Diabetes Mellitus 01/2021 - 12/2020
2	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2016
2	Infections 01/2020 - 07/2014
2	Dermatomyositis (Dermatopolymyositis) 06/2019 - 12/2016
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2018 - 09/2007
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 04/2018 - 01/2006
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2017 - 09/2015
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 09/2017 - 03/2015
2	Lymphoma (Lymphomas) 09/2017 - 03/2015
2	Carcinoma (Carcinomatosis) 01/2016 - 01/2006
2	Graves Disease (Basedow Disease) 12/2015 - 12/2015
2	Hyperplasia 06/2015 - 01/2015
2	Fibrosis (Cirrhosis) 06/2015 - 01/2015
2	Pathologic Constriction (Stenosis) 06/2015 - 01/2015
2	Alzheimer Disease (Alzheimer's Disease) 08/2014 - 01/2014
2	Periodontal Diseases (Periodontal Disease) 08/2013 - 07/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2012 - 01/2011
1	Hypersensitivity (Allergy) 12/2021
1	Microsatellite Instability 08/2021
1	Transient Ischemic Attack 01/2021
1	Myasthenia Gravis 01/2021
1	Myocardial Infarction 01/2021
1	Neuromuscular Junction Diseases 01/2021
1	Dyskinesias (Dyskinesia) 06/2020
1	Parkinson Disease (Parkinson's Disease) 06/2020
1	CHARGE Syndrome 02/2020

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 08/2021 - 07/2003
20	Biomarkers (Surrogate Marker)IBA 02/2021 - 10/2009
10	AntigensIBA 01/2021 - 09/2003
10	poly-U binding splicing factor 60KDaIBA 09/2017 - 02/2006
9	AutoantibodiesIBA 02/2021 - 07/2014
9	AntibodiesIBA 01/2021 - 07/2003
9	Tumor Biomarkers (Tumor Markers)IBA 12/2016 - 03/2004
7	Messenger RNA (mRNA)IBA 02/2020 - 01/2006
6	ElementsIBA 02/2020 - 06/2012
6	Small Interfering RNA (siRNA)IBA 05/2018 - 03/2011
5	Indicators and Reagents (Reagents)IBA 02/2021 - 12/2012
5	Complementary DNA (cDNA)IBA 01/2021 - 04/2018
5	Carrier Proteins (Binding Protein)IBA 02/2020 - 02/2013
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2010
4	ImmunosorbentsIBA 01/2021 - 02/2009
4	CreatinineIBA 12/2015 - 04/2011
4	Cystatin CIBA 12/2015 - 04/2011
4	ProteomeIBA 07/2012 - 03/2004
4	Histone Deacetylase InhibitorsIBA 01/2010 - 11/2005
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 10/2009
3	Peptides (Polypeptides)IBA 01/2021 - 05/2011
3	Immunoglobulin G (IgG)IBA 01/2021 - 07/2014
3	Protein Isoforms (Isoforms)IBA 01/2017 - 03/2004
3	Carcinoembryonic AntigenIBA 01/2016 - 05/2011
3	EnzymesIBA 01/2016 - 02/2009
3	Lipocalin-2IBA 08/2013 - 10/2009
3	romidepsin (FK228)FDA Link 03/2008 - 11/2005
2	Hematoxylin (Haematoxylon)IBA 08/2021 - 06/2015
2	Eosine Yellowish-(YS) (Eosin)IBA 08/2021 - 06/2015
2	Recombinant ProteinsIBA 01/2021 - 04/2018
2	RNA (Ribonucleic Acid)IBA 08/2020 - 03/2015
2	RNA Precursors (Precursor, mRNA)IBA 02/2020 - 06/2012
2	Cyclin EIBA 02/2020 - 05/2018
2	Cadherins (E-Cadherin)IBA 02/2020 - 03/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2018 - 12/2010
2	Annexin A2 (Annexin II)IBA 10/2018 - 12/2012
2	Poly UIBA 05/2018 - 12/2016
2	RNA Splicing FactorsIBA 05/2018 - 12/2016
2	CollagenIBA 06/2015 - 01/2015
2	Apolipoproteins E (ApoE)IBA 08/2014 - 01/2014
2	AlbuminsIBA 01/2014 - 10/2012
2	CarbohydratesIBA 02/2013 - 05/2011
2	Peptide Initiation Factors (Initiation Factor)IBA 03/2011 - 03/2004
2	Vitamin D-Binding ProteinIBA 01/2011 - 10/2009
2	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2011 - 10/2009
2	CarbonIBA 11/2010 - 01/2006
2	Sepharose (Agarose)IBA 02/2006 - 03/2004
2	HLA-DR Antigens (HLA-DR)IBA 01/2006 - 09/2003
1	GlucocorticoidsIBA 12/2021
1	Adaptor Protein Complex 3IBA 01/2021
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 06/2020
1	Monoamine Oxidase (MAO)IBA 06/2020
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 06/2020
1	Levodopa (L Dopa)FDA LinkGeneric 06/2020
1	Dopamine Receptors (Dopamine Receptor)IBA 06/2020
1	Dopamine (Intropin)FDA LinkGeneric 06/2020

Therapy/Procedure

14	Therapeutics 02/2021 - 11/2002
5	Drug Therapy (Chemotherapy) 01/2020 - 11/2002
3	Lasers (Laser) 01/2020 - 05/2011